Kajian Sistematis Efek Anti-oksidan Terapi Akupunktur pada Berbagai Penyakit
DOI:
https://doi.org/10.47861/usd.v1i2.385Keywords:
Homeostasis, Anti-oxidants, Acupuncture Therapy, DiseaseAbstract
Background: Homeostasis is a key concept in life survival. Today, researchers are discovering redox homeostasis as the basis of a wide variety of degenerative diseases. Various methods are studied to maintain redox homeostasis, especially by increasing the body's antioxidant defenses, so that they can prevent and treat various modern diseases, one of which is through acupuncture. Methodology: This article is a systematic review of the therapeutic effects of acupuncture on redox homeostasis published in the PubMed database, Researchgate, CNKI, in the last 10 years. Results: The concept of redox homeostasis is identical to that of Yin-Yang homeostasis in TCM (traditional Chinese medicine). It turns out that acupuncture therapy, which has the effect of maintaining and restoring Yin-Yang homeostasis, has also been shown to have an effect on increasing antioxidant power and reducing body oxidants in various pathological conditions. There are no adverse effects from acupuncture therapy. Conclusion: Acupuncture therapy is effective and safe for maintaining and restoring redox homeostasis, especially for its anti-oxidant effect in various redox reward conditions.
References
Attia, AMM., Ibrahim FAA., El-Latif NAA., Aziz SW., Elwan AM., Aziz AA., Elgendy A., et al. Therapeutic antioxidant and anti-inflammatory effects of laser acupuncture on patients with rheumatoid arthritis. Lasers in Surgery and Medicine. 2016;48:490-497. DOI: 10.1002/lsm.22487.
Du SQ., Wang XR., Zhu W., Ye Y., Yang JW., Ma SM., Ji CS., Liu CZ. Acupuncture inhibits TXNIP-associated oxidative stress and inflammation to attenuate cognitive impairment in vascular dementia rats. CNS Neuroscience & Therapeutics. 2018;24:39-46. DOI: 10.111/cns.12773.
Flieger, J., Flieger, W., Baj, J., & Maciejewski, R. (2021). Antioxidants: Classification, Natural Sources, Activity/Capacity Measurements, and Usefulness for the Synthesis of Nanoparticles. Materials (Basel, Switzerland), 14(15), 4135. https://doi.org/10.3390/ma14154135
Gal, Kristell & Schmidt, Edward & Sayin, Volkan. (2021). Cellular Redox Homeostasis. Antioxidants. DOI: 10. 1377. 10.3390/antiox10091377. https://www.researchgate.net/publication/354211051_Cellular_Redox_Homeostasis
Irianti TT, Kuswandi, Nuranto S, Purwanto (2021). Antioksidan dan kesehatan. UGM PRESS, Yogjakarta. ANTIOKSIDAN DAN KESEHATAN - Tanti Tatang Irianti , Kuswandi , Sindu Nuranto, Purwanto - Google Buku.
Jittiwat, J. Baihui point laser acupuncture ameliorates cognitive impairment, motor deficit, and neuronal loss partly via antioxidant and anti-inflammatory effects in an animal model of focal ischemic stroke. Hindawi Evidence-Based Complementary and Alternative Medicine. 2019;1204709:1-9. DOI: 10.1155/2019/1204709.
Kandarakis, ED., Papalou O., Kandaraki EA., Kassi G. Nutrition as a mediator of oxidative stress in metabolic and reproductive disorders in women. European Journal of Endocrinology. 2017;176:R79-R99. DOI: 10. 1530/EJE-16-0616.
Leung SB., Zhang H., Lau CW., Lin ZX. Attenuation of blood pressure in spontaneously hypertensive rats by acupuncture was associated with reduced oxidative stress and improvement from endothelial dysfunction. Chinese Medicine. 2016;11:38:1-18. DOI: 10.1186/s13020-016-0110-0.
LEE BH, Lee YJ, Zhao RJ, Kim YW, et al, Antioxidant effects of acupuncture in morphine plus acetaminophen injured rat liver, Integrative Medicine Research, Volume 4, Issue 1, Supplement, 2015, Pages 70-71, ISSN 2213-4220, https://doi.org/10.1016/j.imr.2015.04.091. (https://www.sciencedirect.com/science/article/pii/S2213422015001158)
Lee CI., Lee HJ., Lee YK., Lim SC. The effects of LR3 and SP6 acupuncture on renal damage in Streptozotocin-induced diabetic mice. The Acupuncture. 2015;32:3:41-51. DOI: 10.13045/acupunct.2015037.
Lee, Y. J. Acupuncture inhibits liver injury induced by morphine plus acetaminophen through an antioxidant system. European Journal of Integrative Medicine. 2016;8:3:204-212. DOI: 10.1016/j.eujim.2015.12.009.
Lin, LT., Li H., Yang JW., Zeng XH., He T., Shi GX., Liu CZ. Acupuncture mechanism on oxidative stress in various diseases. Science Foundation in China. 2015;23:2:60-65.
LIU Jian, LI Yinhong, WAN Jiwei & GAO Ting. (2015). Antioxidant mechanism of acupuncture antihypertensive from the perspective of oxidation/antioxidant enzymes. Liaoning Journal of Traditional Chinese Medicine(08),1543-1545. doi:10.13192/j.issn.1000-1719.2015.08.067. The Antioxidant Mechanism of Acupuncture Antihypertensive from Oxidation/antioxidant Enzymes Perspective - CNKI
Olsen, L. F., Issinger, O. G., & Guerra, B. (2013). The Yin and Yang of redox regulation. Redox report : communications in free radical research, 18(6), 245–252. https://doi.org/10.1179/1351000213Y.0000000059
Ou, B., Huang, D., Hampsch-Woodill, M., & Flanagan, J. A. (2003). When east meets west: the relationship between yin-yang and antioxidation-oxidation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 17(2), 127–129. https://doi.org/10.1096/fj.02-0527hyp
Rahman T., Hosen I., Islam T., Shekhar HD. Oxidative stress and human health. Advances in Bioscience and Biotechnology. 2012;3:997-1019. DOI: 10.4236/abb.2012.327123.
Ren Zeqin. (2022). Based on FoxO/Wnt signaling pathway, anti-oxidative stress prevention and treatment of postmenopausal osteoporosis by strengthening the spleen and kidneys and strengthening bones (Ph.D. dissertation, Nanjing University of Chinese Medicine). https://kns.cnki.net/KCMS/detail/detail.aspx?dbname=CDFDTEMP&filename=1023005363.nh
Sharma, S.. (2017). Antioxidants: Their health benefits. Available at: https://www.researchgate.net/publication/320623406_Antioxidants_Their_health_benefits [accessed May 28 2023].
Shi GX., Wang XR., Yan CQ, He T., Yang JW., Zeng XH., Xu Q., et al. Acupuncture elicits neuroprotective effects by inhibiting NADPH oxidase-mediated reactive oxygen species production in cerebral ischemia. Scientific Reports. 2016;5:17981:1-10.
Siu FKW., Lo SCL., Leung MCP. Electro-acupuncture potentiates the disulfide-reducing activities of the thioredoxin system by increasing thioredoxin expression in ischemia-reperfused rat brains. Life Sciences 2005; 77:4:386-399. DOI: 10.1016/j.lfs.2004.10.069.
Su XT., Wang L, Ma SM, Cao Y, Yang NN, Lin, LL et al. (2020). Mechanisms of Acupuncture in the Regulation of Oxidative Stress in Treating Ischemic Stroke. Oxidative medicine and cellular longevity, 2020, 7875396. https://doi.org/10.1155/2020/7875396
Wang, XR., Shi GX., Yang JW. Acupuncture ameliorates cognitive impairment and hippocampus neuronal loss in experimental vascular dementia through Nrf-2 mediated antioxidant response. Free Radical Biology and Medicine. 2015;89:1077-1084. DOI: 10.1016/j.freeradbiomed. 2015.10.426.
Zeng XH et al (2014). Acupuncture mechanism and redox equilibrium. Hindawi Evidence-Based Complementary and Alternative Medicine. 2014;483294:1-4. DOI:10.1155/2014/483294.
Zhai Heng, Zhang Baowen & Yuan Xun. (2016). Effects of acupuncture on behavior and antioxidant capacity of mice with chronic fatigue syndrome. Contemporary Chinese Medicine (25), 12-15. doi:CNKI:SUN:ZGUD.0.2016-25-003. Effects of acupuncture of different acupiont groups on behaviors and antioxidant capacities in mice with chronic fatigue syndrome - CNKI
Zuo, J., Zhang, Z., Luo, M., Zhou, L., Nice, E. C., Zhang, W., Wang, C., & Huang, C. (2022). Redox signaling at the crossroads of human health and disease. MedComm, 3(2), e127. https://doi.org/10.1002/mco2.127
